Complications of antiretroviral therapy initiation in hospitalised patients with HIV-associated tuberculosis.
Identifieur interne : 002990 ( Main/Exploration ); précédent : 002989; suivant : 002991Complications of antiretroviral therapy initiation in hospitalised patients with HIV-associated tuberculosis.
Auteurs : Helen Van Der Plas [Afrique du Sud] ; Graeme Meintjes ; Charlotte Schutz ; Rene Goliath ; Landon Myer ; Dorothea Baatjie ; Robert J. Wilkinson ; Gary Maartens ; Marc MendelsonSource :
- PloS one [ 1932-6203 ] ; 2013.
Descripteurs français
- KwdFr :
- MESH :
- effets indésirables : Agents antiVIH.
- traitement médicamenteux : Infections opportunistes liées au SIDA.
- usage thérapeutique : Agents antiVIH.
- Adulte, Femelle, Humains, Mâle, République d'Afrique du Sud, Tuberculose, Études de cohortes, Études prospectives.
- Wicri :
- geographic : Afrique du Sud.
English descriptors
- KwdEn :
- MESH :
- chemical , adverse effects : Anti-HIV Agents.
- geographic : South Africa.
- complications : Tuberculosis.
- drug therapy : AIDS-Related Opportunistic Infections.
- chemical , therapeutic use : Anti-HIV Agents.
- Adult, Cohort Studies, Female, Humans, Male, Prospective Studies.
Abstract
HIV-associated tuberculosis is a common coinfection in Sub-Saharan Africa, which causes high morbidity and mortality. A sub-set of HIV-associated tuberculosis patients require prolonged hospital admission, during which antiretroviral therapy initiation may be required. The aim of this study was to document the causes of clinical deterioration of hospitalised patients with HIV-associated tuberculosis starting antiretroviral therapy in order to inform healthcare practice in low- to middle-income countries.
DOI: 10.1371/journal.pone.0054145
PubMed: 23408935
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">HIV-associated tuberculosis is a common coinfection in Sub-Saharan Africa, which causes high morbidity and mortality. A sub-set of HIV-associated tuberculosis patients require prolonged hospital admission, during which antiretroviral therapy initiation may be required. The aim of this study was to document the causes of clinical deterioration of hospitalised patients with HIV-associated tuberculosis starting antiretroviral therapy in order to inform healthcare practice in low- to middle-income countries.</div>
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<affiliations><list><country><li>Afrique du Sud</li>
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<tree><noCountry><name sortKey="Baatjie, Dorothea" sort="Baatjie, Dorothea" uniqKey="Baatjie D" first="Dorothea" last="Baatjie">Dorothea Baatjie</name>
<name sortKey="Goliath, Rene" sort="Goliath, Rene" uniqKey="Goliath R" first="Rene" last="Goliath">Rene Goliath</name>
<name sortKey="Maartens, Gary" sort="Maartens, Gary" uniqKey="Maartens G" first="Gary" last="Maartens">Gary Maartens</name>
<name sortKey="Meintjes, Graeme" sort="Meintjes, Graeme" uniqKey="Meintjes G" first="Graeme" last="Meintjes">Graeme Meintjes</name>
<name sortKey="Mendelson, Marc" sort="Mendelson, Marc" uniqKey="Mendelson M" first="Marc" last="Mendelson">Marc Mendelson</name>
<name sortKey="Myer, Landon" sort="Myer, Landon" uniqKey="Myer L" first="Landon" last="Myer">Landon Myer</name>
<name sortKey="Schutz, Charlotte" sort="Schutz, Charlotte" uniqKey="Schutz C" first="Charlotte" last="Schutz">Charlotte Schutz</name>
<name sortKey="Wilkinson, Robert J" sort="Wilkinson, Robert J" uniqKey="Wilkinson R" first="Robert J" last="Wilkinson">Robert J. Wilkinson</name>
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<country name="Afrique du Sud"><noRegion><name sortKey="Van Der Plas, Helen" sort="Van Der Plas, Helen" uniqKey="Van Der Plas H" first="Helen" last="Van Der Plas">Helen Van Der Plas</name>
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